Home »
Tablets
» Instant Coating (Ready Mix to Coat)
Instant Coating (Ready Mix to Coat)
Lorem ipsum dolor sit amet, consectetuer adipiscing
elit, sed diam nonummy nibh euismod tincidunt adipiscing elit, sed diam
nonummy nibh euismod tincidunt.Lorem ipsum dolor sit amet, consectetuer
adipiscing elit, sed diam nonummy nibh euismod tincidunt adipiscing elit,
sed diam nonummy nibh euismod tincidunt.
Range Of Speciality Products s
 |
| No. |
Products |
Usage |
% Require* |
| 1 |
Procoat UFC |
Universal readymix powder for
aqueous, Hydro alcoholic or solvent base film coating. |
1.5 to 2.5% for solvent system.
1.2 to 2.0% for aqueous system. |
| 2 |
Procoat AFC |
Readymix powder for aqueous base
film coating. |
1.2 to 2.0% |
| 3 |
Procoat SFC |
Readymix powder for solvent base
film coating. |
1.5 to 2.5% |
| 4 |
Procoat FCS |
Readymix powder for aqueous,
Hydro alcoholic or solvent base film coating. |
1.5 to 2.5% for solvent system.
1.2 to 2.0% for aqueous system. |
| 5 |
Procoat WT |
Readymix (white) cost effective
powder for aqueous, Hydro alcoholic or solvent base film coating.
Color has to incorporate by customer as per requirement. |
1.5 to 2.5% for solvent system.
1.2 to 2.0% for aqueous system. |
| 6 |
Procoat AWT |
Readymix (white) powder specially
designed for low costing aqueous film coating. Color has to
incorporate by customer as per requirement. |
1.2 to 2.0% |
| 7 |
Procoat SR |
Readymix powder for sustain
release formulations. |
Depend upon nature of drug. |
| 8 |
Procoat ECC |
Cellulose Acetate Phthalate (CAP)
base readymix powder for solvent base enteric coating. |
6 - 10% |
| 9 |
Procoat ECH |
Hydroxyl Propyl Methyl Cellulose
Phthalate (HPMCP) base readymix powder for solvent base enteric
coating. |
6 - 8% |
| 10 |
Procoat ECM |
Methacylic acid co-polymer base
readymix powder for aqueous or solvent base enteric coating. |
6 - 8% |
| 11 |
Procoat SH |
Readymix powder for polishing of
tablet. |
0.5 - 1.0% |
| 12 |
Procoat MB |
Readymix powder for moisture
barrier coating on moisture sensitive drug. It increases stability
of drug. |
3 - 5% |
|
|
» Storage : Store in cool & dry
place in tightly closed condition
» Packing : 1 kg, 5 kg, 25 kg in corrugated box / Plastic jar
Film Coating By Procoat ( Solvent System )
|
| No. |
How to Use |
Solvent System |
Aqueous System |
| 1 |
Grades of Procoat Applicable |
Procoat UFC/SFC/FCS/WT |
Procoat UFC/AFC/FCS/WT/AWT |
| 2 |
% of Procoat Required |
1.5 - 2.5% w/w |
1.2 - 2.0% w/w |
| 3 |
Vehicle Recommended |
Iso Propyl Alcoho (IPA) /
Methanol 40% w/w Methylene Di Chloride (MDC) 60% w/w |
De Mineralised Water (D.M. Water)
100% w/w |
| 4 |
Solid % in Solution |
5 - 7% w/w |
12 - 15% w/w |
| 5 |
Example |
Batch Size : 35 Kgs,
Tablets
Punch Size : 10/32" (8mm approx)
Av. Wt. Of Tablet : 200 Mgs.
PROCOAT require :
For 2% wt. Gain = 0.7 Kgs
Formula :
PROCOAT : 0.70 Kgs.
M.D.C. : 7.98 Kgs.
I.P.A : 5.32 Kgs.
_____________
Total : 14.00 Kgs.
Solid % in solution = 5% w/w |
Batch Size : 35 Kgs,
Tablets
Punch Size : 10/32" (8mm approx)
Av. Wt. of Tablet : 200 Mgs.
PROCOAT require :
For 2% wt. Gain = 0.7 Kgs
Formula :
PROCOAT : 0.70 Kgs.
D.M.Water. : 4.90 Kgs.
_____________
Total : 5.60 Kgs.
Solid % in solution = 12.5% w/w |
| 6 |
Method of Preparation |
¤ Take total
quantity of solvent in a container. Stirr it by propeller type of
stirrer to form a vortex.
¤ Add PROCOAT in a fine stream. If require increase speed to
maintain vortex.
¤ After complete addtion of PROCOAT continue stirring for 45
minutes.
¤ Filter the solution through 200 # bolting cloth. |
¤ Take D.M. water (heated up to 600C) in a container. Stirr it
by propeller type of stirrer to form a vortex.
¤ Add PROCOAT ina fine stream. If require increase speed to
maintain vortex.
¤ After complete addition of PROCOAT continue stirring for 45
minutes.
¤ Filter the solution thourgh 200# bolting cloth. |
| 7 |
Tablet Parameter |
Hardness - NLT 30 Kg/Cm2
Friability - NMT 0.5% |
Hardness - NLT 4.0 Kg/Cm2
Friability - NMT 0.5% |
| 8 |
Process Parameter (For 36"
coating Pan) |
Air Pressure - 3 - 4 Kg/Cm2
Inlet Temp. - 60 - 700C
Bed Temp. - 35 - 400C
Pan RPM - 8 - 12 |
Air Pressure - 4 - 5 Kg/Cm2
Inlet Temp. - 70 - 800C
Bed Temp. - 35 - 400C
Pan RPM - 8 - 12 |
|
|
Film Coating By Procoat ( Hydro-Alcoholic System )
|
| No. |
How to Use |
Hydro-Alcoholic System |
| 1 |
Grades of Procoat
Applicable |
UFC / FCS / WT |
| 2 |
% of Procoat Required |
2 - 2.5% w/w |
| 3 |
Vehicle Recommended |
Iso Propyl Alcohol (IPA) 50% w/w
De Mineralised Water (D.M. WATER) 50% w/w |
| 4 |
Solid % in Solution |
9 - 10% w/w |
| 5 |
Example |
Batch Size : 35 Kgs,
Tablets
Punch Size : 10/32" (8mm approx)
Av. Wt. of Tablet : 200 Mgs.
PROCOAT require for 2% wt. Gain = 0.7 Kgs
Formula :
PROCOAT : 00.700 Kgs.
D.M. WATER : 03.538 Kgs.
I.P.A : 03.538 Kgs.
_____________
Total : 07.776 Kgs.
Solid % in solution = 9% w/w |
| 6 |
Method of Preparation |
¤ Take IPA in a
container under stirring.
¤ To this slowly add PROCOAT in it.
¤ Stir it for about 5 minutes.
¤ Now slowly add D.M. Water to it.
¤ Continue stirring for 45 minutes.
¤ Filter the suspension through 200# bolting cloth. |
| 7 |
Tablet Parameter |
Hardness - NLT 4.0 Kg/Cm2
Friability - NMT 0.5% |
| 8 |
Process Parameter (For 36"
coating Pan) |
Air Pressure : 3 - 4 Kg/Cm2
Inlet Temp. : 60 - 700C
Bed Temp. : 35 - 400C
Pan RPM : 8 - 12 |
|
|
Applications
- Moisture sensitive drug : Calcium Carbonate, Ibuprofen,
Certrizine, Famotidine, Ayurvedic products, Ranitidine, Vitamins,
Ethambutol, Rifampicin etc.
- Other Drugs : Diltiazem, Norfloxacin, Ciprofloxacin,
Metroniadazole, tinidazole, Ornidazole, Chloroquine Phosphate,
Roxithromycin,Azithromycin, Gatifloxacin, Erythromycin, Cimetidine,
Levofloxacin, Sildinafil Citrate etc.
Coating Parameters ( For Aqueous film coating )
|
| No. |
Coating Pan |
12" Conv. |
24" Conv. |
36" Conv. |
48" Conv./Auto |
60" Conv./Auto |
| 1 |
Pan Speed (RPM) |
15-20 |
10-14 |
8-12 |
5-8 |
3-6 |
| 2 |
Air Pressure (kg/cm2) |
2-2.5 |
3-4 |
4-5 |
5-6 |
5-6 |
| 3 |
Blower Air Volume (CFM) |
30 |
200-300 |
700-1000 |
1300-2200 |
4000-5500 |
| 4 |
Solid Content (%) |
12-15 |
12-15 |
12-15 |
12-15 |
12-15 |
| 5 |
Baffles |
4 |
4 |
4 |
4 |
4 |
| 6 |
Tablet Weight |
1 kg |
20 kg |
45 kg |
100 kg |
200 kg |
| 7 |
Bed Temperature (0C) |
35-40 |
35-40 |
35-40 |
35-42 |
35-42 |
| 8 |
Spray Nozzle (mm) |
1 |
1.5 |
1.5 |
1.8 |
1.8 |
| 9 |
No of Spray Gun |
1 |
1 |
1 |
2/3 |
3/4 |
| 10 |
Inlet Air Temperature (0C) |
70 |
70 |
70-80 |
75-85 |
75-85 |
|
|
Coating Parameters ( For Solvent film coating )
|
| No. |
Coating Pan |
12" Conv. |
24" Conv. |
36" Conv. |
48" Conv./Auto |
60" Conv./Auto |
| 1 |
Pan Speed (RPM) |
15-20 |
10-14 |
8-12 |
5-8 |
3-6 |
| 2 |
Air Pressure (kg/cm2) |
2-2.5 |
2.0-3.0 |
3.0-4.0 |
3.5-4.5 |
4.0-5.0 |
| 3 |
Blower Air Volume (CFM) |
30 |
200-300 |
700-1000 |
1300-2200 |
4000-5500 |
| 4 |
Solid Content (%) |
5-7 |
5-7 |
5-7 |
5-7 |
5-7 |
| 5 |
Baffles |
4 |
4 |
4 |
4 |
4 |
| 6 |
Tablet Weight |
1 kg |
20 kg |
45 kg |
100 kg |
200 kg |
| 7 |
Bed Temperature (0C) |
35-40 |
35-40 |
35-40 |
35-42 |
35-42 |
| 8 |
Spray Nozzle (mm) |
1 |
1.5 |
1.5 |
1.8 |
1.8 |
| 9 |
No of Spray Gun |
1 |
1 |
1 |
2/3 |
3/4 |
| 10 |
Inlet Air Temperature (0C) |
60 |
60 |
60-70 |
70-80 |
70-80 |
|
|
Ideal Requirement of best Coating Facility
|
| Spray Gun |
Bullose 230, Pilot Type 59 |
| Stand |
for fixing spray gun |
| Air Compressor |
with pressure gauge and air
filters. Air pressure available should be 3 - 6 kg/cm2 |
| Peristaltic Pump |
Electrolab PP 20IV - with 4 - 6
mm ID silicon tube this ensure uniform spray through out process
|
| Weighing Balance |
Solution to be kept on balance
for calculating spray rate/min |
|
|
Process Variables to Control During Coating
- Revolution Per Minute (RPM) of Pan
- Spray Rate
- Spray pattern and distance between spray gun and tablet bed
- Inlet, Outlet and Bed Temperature
- Air Pressure
Important Hints
- Provide gentle stirring to the coating solution during spraying to
prevent settling of some heavy pigments present in the solution.
- While using PROCOAT WT (white), prepare the solution 24 hrs. advance
to get best whiteness.
- Some time grayish spots develops on tablet during coating due to
friction between pan and tablets. In such condition coat the internal
surface of pan by the same solution, dry the pan and then load the
tablet for coating.
- PROCOAT can be used in any coating machines such as Conventional
Coating Pan, Autocoater (like Ganson, Neocoat, Accella Coata etc.) &
Fluid Bed Coater.
Technical Support
We have tried to explain our level best in
literature. But process variables to be made as per coating facilities at
customer's premises. Our technical staff is ready to serve our valuable
customers by explaining & demonstrating entire coating operation.
Advantages
- Easy to prepare coating solution
- High solid content can be sprayed, reducing process time
- Less percentage of material require, reducing process time
- Less inventory, white base available
- Smooth & shiny film
- Sigh adhesion property of film
- Fixed source of raw material, ensures batch to batch uniformity in
coating
- No colour variation
- High colour stability
